LBL1

Overview

LBL1 is a Lamin A inhibitor with a K d of 5.11 μM for LA (1-387). LBL1 directly binds to Lamin A and disrupts the Lamin A- Rad51 interaction, accelerates proteasome-mediated Rad51 degradation, and induces DNA double-strand breaks. LBL1 induces Apoptosis . LBL1 serves as a chemical tool for studying lamin biology and the post-translational regulation of Rad51 . LBL1 can be used in studies related to breast cancer and non-small cell lung cancer .

Application

Products | Products > Disease Areas > Respiratory Cancer | Products > Disease Areas > Breast Cancer | Products > Disease Areas > Non-Small Cell Lung Cancer | Products > Disease Areas > Cancer | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Lung Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Signaling Pathways > DNA/RNA Synthesis | Products > Signaling Pathways > RAD51 | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-115533
• CAS No.: 1605301-58-3
• Molecular Formula: C21H15N5O
• Molecular Weight: 353.38
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source