NAE-IN-M22

Overview

NAE-IN-M22 is a potent, selective and reversible inhibitor of NEDD8 activating enzyme (NAE) , with potency in micromolar range. NAE-IN-M22 inhibits multiple cancer cell lines and induces apoptosis in A549 cells. NAE-IN-M22 also can inhibit tumor growth in vivo.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Digestive System Inflammation | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-115537
• CAS No.: 864420-54-2
• Molecular Formula: C20H24Cl2N2
• Molecular Weight: 363.32
• Purity: 99.94%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (5.72 mM); Clear solution
• Availability: In-stock

Source

Original product source