P62-mediated mitophagy inducer

Overview

P62-mediated mitophagy inducer (PMI) is a P62 -mediated mitophagy activator . P62-mediated mitophagy inducer activates mitochondrial autophagy without recruitment of Parkin or collapse of the mitochondrial membrane potential and remains active in cells lacking a fully functional PINK1/Parkin pathway. P62-mediated mitophagy inducer serves as a pharmacological tool to study the molecular mechanisms of mitosis , avoiding toxicity and some of the non-specific effects associated with the sudden dissipation of mitochondria lacking membrane potential.

Application

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Product Information

• Catalog No.: HY-115576
• CAS No.: 1809031-84-2
• Molecular Formula: C14H9IN4O2
• Molecular Weight: 392.15
• Purity: 99.54%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 1.25 mg/mL (3.19 mM); Clear solution
• Availability: In-stock

Source

Original product source