KS15

Overview

KS15 is an inhibitor of the interactions between cryptochromes (CRYs: CRY1 and CRY2) and the CLOCK:BMAL1 heterodimer . KS15 impairs the feedback actions of CRYs on E-box-dependent transcription (EC 50 =4.9 μM) by CLOCK:BMAL1 heterodimer, an indispensable transcriptional regulator of the mammalian circadian clock. Anti-proliferative activity.

Application

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Product Information

• Catalog No.: HY-115672
• CAS No.: 1033781-20-2
• Molecular Formula: C20H22BrNO4
• Molecular Weight: 420.30
• Purity: 99.46%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: 2.5 mg/mL (5.95 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source