Okadaic acid ammonium salt

Overview

Okadaic acid ammonium salt, a marine toxin, is an inhibitor of protein phosphatases (PP) . Okadaic acid ammonium salt has a significantly higher affinity for PP2A ( IC 50 =0.1-0.3 nM), and inhibits PP1 ( IC 50 =15-50 nM), PP3 ( IC 50 =3.7-4 nM), PP4 ( IC 50 =0.1 nM), PP5 ( IC 50 =3.5 nM), but does not inhibit PP2C. Okadaic acid ammonium salt increases of phosphorylation of a number of proteins by inhibiting PP, and acts as a tumor promoter. Okadaic acid ammonium salt induces tau phosphorylation.

Application

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Product Information

• Catalog No.: HY-115760
• CAS No.: 175522-42-6
• Molecular Formula: C44H71NO13
• Molecular Weight: 822.03
• Purity: 99.9%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source