EGFR/BRAF-IN-1

Overview

EGFR/BRAF-IN-1 (compound 21), a 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivative, is a potent EGFR/BRAF inhibitor with an IC 50 of 45 nM for BRAF V600E . EGFR/BRAF-IN-1 inhibits cancer cell proliferation (GI 50 =35 nM). EGFR/BRAF-IN-1 shows good antioxidant activity.

Application

Products | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > EGFR | Products > Signaling Pathways > Raf

Product Information

• Catalog No.: HY-115933
• CAS No.: 2906174-89-6
• Molecular Formula: C26H28ClN3O4
• Molecular Weight: 481.97
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source