Selatinib is an orally active EGFR and HER2 tyrosine kinase inhibitor with IC 50 values of 13.0 nM and 8.5 nM, respectively. Selatinib undergoes oxidative metabolism in vivo to produce Lapatinib ( HY-50898 ). Selatinib inhibits the growth of breast, gastric and ovarian tumors. Selatinib can be used in research related to gastric cancer , breast cancer and ovarian cancer .
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