ML753286

Overview

ML753286 is an orally active and selective BCRP (Breast cancer resistance protein) inhibitor with an IC 50 of 0.6 μM. ML753286 has high permeability and low to medium clearance in rodent and human liver S9 fractions, and is stable in plasma cross species.

Application

Products | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > BCRP

Product Information

• Catalog No.: HY-116494
• CAS No.: 1699720-89-2
• Molecular Formula: C20H25N3O3
• Molecular Weight: 355.43
• Purity: 99.98%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 2.5 mg/mL (7.03 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source