YM-359445 dihydroxybutanedioate

Overview

YM-359445 dihydroxybutanedioate is an orally active VEGFR2 tyrosine kinase inhibitor, with an IC 50 of 8.5 nM. YM-359445 dihydroxybutanedioate shows a complete inhibition of vascular permeability induced by VEGF . YM-359445 dihydroxybutanedioate shows antitumor activity against both lung cancer and Paclitaxel ( HY-B0015 )-resistant colon cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Signaling Pathways > VEGFR

Product Information

• Catalog No.: HY-117039
• CAS No.: 1020067-28-0
• Molecular Formula: C32H34N6O8S
• Molecular Weight: 662.71
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source