AN-7 is an orally active histone deacetylase ( HDAC ) inhibitor that induces histone hyperacetylation and differentiation in vitro and in vivo, and inhibits the proliferation of human prostate 22Rv1 cancer cells. AN-7 can increase the expression of the pro-apoptotic protein Bax , reduce the expression of the anti-apoptotic protein Bcl-2 , and promote apoptosis by activating caspase-3 , and can be used in the study of prostate cancer .
Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > HDAC | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > Bcl-2 Family
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