FAK-IN-16

Overview

FAK-IN-16 (compound OXA-11) is an orally active, selective focal adhesion kinase ( FAK ) inhibitor with an IC 50 of 1.2 pM. FAK-IN-16 inhibits FAK phosphorylation at pFAK[Y397] and pFAK[Y861]. FAK-IN-16 slows tumor growth and reduces tumor vascularity, invasion. FAK-IN-16 potentiates effects of Cisplatin ( HY-17394 ) on tumor cell proliferation and apoptosis in vitro and anti-tumor actions in mice.

Application

Products | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > FAK

Product Information

• Catalog No.: HY-117836
• CAS No.: 1257994-15-2
• Molecular Formula: C37H49F3N7O5P
• Molecular Weight: 759.80
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source