T-3861174

Overview

T-3861174 is an inhibitor of prolyl-tRNA synthetase ( PRS , Aminoacyl-tRNA Synthetase ) without completely inhibiting its translation process. T-3861174 activates the GCN2-ATF4 pathway and induces death in multiple tumor cell lines, including SK-MEL-2. T-3861174 demonstrated significant antitumor activity in multiple xenograft models without significantly affecting body weight.

Application

Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Aminoacyl-tRNA Synthetase

Product Information

• Catalog No.: HY-117938
• CAS No.: 2209057-94-1
• Molecular Formula: C26H25FN6O2
• Molecular Weight: 472.51
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source