Pentamethoxymorin (MRS923) is a selective b reast cancer resistance protein (BCRP/ABCG2) inhibitor . Pentamethoxymorin shows selectivity for BCRP over P-gp and MRP1. Pentamethoxymorin inhibits MDCK BCRP cells with IC 50 vaues of 5.98 μM and 5.94 μM in Hoechst 33342 ( HY-15559 ) assay and Pheophorbide A ( HY-125665 ) assay, respectively. Pentamethoxymorin can be used for the study of ccancer.
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