ML356 (Compound 16) is an inhibitor for fatty acid synthase ( FAS ), that inhibits the thioesterase domain of FAS ( FAS TE ) with an IC 50 of 0.334 μM, and blocks the de novo palmitate synthesis in PC-3 cell with an IC 50 of 20 μM. ML356 exhibits good membrane permeability, and good stability in human and mouse plasma.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Fatty Acid Synthase (FASN)
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