UK-101

Overview

UK-101 is a potent and selective immunoproteasome β1i (LMP2) inhibitor with an IC 50 value of 104 nM, displays 144- and 10-fold selectivity over β1c ( IC 50 =15 μM) and β5 subunit ( IC 50 =1 μM), respectivey. UK-101 induces cell apoptosis and can be used for the study of prostate cancer .

Application

Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Proteasome | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-119037
• CAS No.: 1000313-40-5
• Molecular Formula: C25H48N2O5Si
• Molecular Weight: 484.74
• Purity: 99.35%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (5.16 mM); Clear solution
• Availability: In-stock

Source

Original product source