Apratastat

Overview

Apratastat (TMI-005) is an orally active, non-selective and reversible TACE/MMPs inhibitor, can inhibit inhibit the release of TNF-α . Apratastat has the potential to overcome radiotherapy-resistance in non-small cell lung cancer (NSCLC). Apratastat is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Application

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Product Information

• Catalog No.: HY-119307
• CAS No.: 287405-51-0
• Molecular Formula: C17H22N2O6S2
• Molecular Weight: 414.50
• Purity: 99.28%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (6.03 mM); Clear solution
• Availability: In-stock

Source

Original product source