BRM/BRG1 ATP Inhibitor-1

Overview

BRM/BRG1 ATP Inhibitor-1 (compound 14) is an orally active allosteric dual brahma homolog (BRM) /SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 2 (SMARCA2) and brahma related gene 1 (BRG1)/SMARCA4 ATPase activity inhibitor, both IC 50 s are below 0.005 µM. BRM/BRG1 ATP Inhibitor-1 has anticancer activity.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > SWI/SNF Complex

Product Information

• Catalog No.: HY-119374
• CAS No.: 2270879-17-7
• Molecular Formula: C11H9F3N4O2S
• Molecular Weight: 318.27
• Purity: 99.72%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.08 mg/mL (6.54 mM); Clear solution
• Availability: In-stock

Source

Original product source