ROCK inhibitor-2

ROCK inhibitor-2
  • CAS No.:1127308-52-4
  • Grade:99.92%
  • Formula:C21H20N2O2
  • M.W.:332.40
  • Solvent:≥ 5 mg/mL (15.04 mM); Clear solution

Overview

ROCK inhibitor-2 (compound 6) is a selective dual inhibitor of ROCK1 and ROCK2 , with IC 50 values of 160 nM and 21 nM, respectively. ROCK inhibitor-2 inhibits pMYPT1 with IC 50 of 75 nM. ROCK inhibitor-2 exhibits antitumor activity.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Pulmonary Disease | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Lung Fibrosis | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cardiovascular Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > ROCK

Product Information

  • Catalog No.: HY-119937
  • CAS No.: 1127308-52-4
  • Molecular Formula: C21H20N2O2
  • Molecular Weight: 332.40
  • Purity: 99.92%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
  • Solubility: ≥ 5 mg/mL (15.04 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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