DD1

Overview

DD1, a proteasome inhibitor, targets Bax activation and P70S6K degradation during acute myeloid leukemia (AML) apoptosis . DD1 induces apoptosis in the caspase-dependent manner. DD1 induces mitochondrial membrane depolarization and Bad dephosphorylation.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Proteasome | Products > Signaling Pathways > Ribosomal S6 Kinase (RSK) | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-120035
• CAS No.: 187585-11-1
• Molecular Formula: C16H14N2O3
• Molecular Weight: 282.29
• Purity: 99.40%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (8.86 mM); Clear solution
• Availability: In-stock

Source

Original product source