KMH-233

Overview

KMH-233, a potent, reversible and selective inhibitor of l-type amino acid transporter LAT1/SLC7A5 , inhibits the uptake of LAT1 substrate, l-leucin (IC 50 =18 μM) as well as cell growth. KMH-233 significantly potentiates the efficacy of Bestatin and Cisplatin even at low concentrations (25 μM).

Application

Products | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Amino acid Transporter

Product Information

• Catalog No.: HY-120139
• CAS No.: 1941174-13-5
• Molecular Formula: C32H25N7O5
• Molecular Weight: 587.58
• Purity: 99.75%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (4.25 mM); Clear solution
• Availability: In-stock

Source

Original product source