DRI-C21045

Overview

DRI-C21045 (compound 10) is a potent and selective inhibitor of the CD40-CD40L costimulatory protein-protein interaction (PPI) with an IC 50 of 0.17 μM. DRI-C21045 shows concentration-dependent inhibition of the activation of NF-κB and B cell proliferation all induced by CD40L with IC 50 s of 17.1 μM and 4.5 μM, respectively.

Application

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Product Information

• Catalog No.: HY-120323
• CAS No.: 2101765-81-3
• Molecular Formula: C32H24N2O7S
• Molecular Weight: 580.61
• Purity: 98.11%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: 0.5 mg/mL (0.86 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source