BMS-243117

Overview

BMS-243117 is a potent, and selective benzothiazole based p56 Lck inhibitor with an IC 50 of 4 nM. BMS-243117 inhibits anti-CD3/anti-CD28 induced PBL (human peripheral blood T-cells) proliferation with an IC 50 of 1.1 μM. BMS-243117 binds in an extended conformation to the ATP-binding site of Lck .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Src

Product Information

• Catalog No.: HY-120622
• CAS No.: 225521-80-2
• Molecular Formula: C20H21ClN4O2S
• Molecular Weight: 416.92
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source