BMS-605541 is a selective and orally active inhibitor of VEGFR-2 kinase with an IC 50 value of 23 nM and K i value of 49 nM. BMS-605541 inhibits the activity of Flk-1 , VEGFR-1 and PDGFR-β with IC 50 values of 40 nM, 400 nM and 200 nM, respectively. BMS-605541 can be used for cancer research.
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