DS-5272

Overview

DS-5272 is an orally acitve inhibitor for p53-MDM2 with an IC 50 of 20 nM. DS-5272 inhibits the proliferation of SJSA-1 (wildtype p53, IC 50 =0.17 μM) and DLD-1 (mutant p53). DS-5272 arrest the cell cycle, and induces apoptosis in SJSA-1. DS-5272 exhibits antitumor efficacy in mice.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > MDM-2/p53 | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-120667
• CAS No.: 1235575-97-9
• Molecular Formula: C34H38Cl2F2N6O2S
• Molecular Weight: 703.67
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source