CCT077791 is a PCAF ( IC 50 : 7.3 μM (FlashPlate); 2.2 μM (Filter assay)) and p300 histone acetyltransferase inhibitor. CCT077791 reduces total acetylation of histones H3 and H4, levels of specific acetylated lysine marks, and acetylation of α-tubulin . CCT077791 can be used in the research of colorectal cancer .
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