7BIO

Overview

7BIO (7-Bromoindirubin-3-Oxime) is the derivate of indirubin. 7BIO (7-Bromoindirubin-3-Oxime) has inhibitory effects against cyclin-dependent kinase-5 ( CDK5 ) and glycogen synthase kinase-3β ( GSK3β ). 7BIO (7-Bromoindirubin-3-Oxime) inhibits Aβ oligomer-induced neuroinflammation, synaptic impairments, tau hyper-phosphorylation, activation of astrocytes and microglia, and attenuates Aβ oligomer-induced cognitive impairments in mice [1] .

Application

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Product Information

• Catalog No.: HY-121035
• CAS No.: 916440-85-2
• Molecular Formula: C16H10BrN3O2
• Molecular Weight: 356.17
• Purity: 99.20%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (7.02 mM); Clear solution
• Availability: In-stock

Source

Original product source