INI-43

Overview

INI-43 is an inhibitor of Kpnβ1 , interfering with the nuclear localization of Kpnβ1 and known Kpnβ1 cargo proteins, NFAT, NFκB, AP-1 , and NFY. INI-43 can inhibit the proliferation of cancer cells, cause G 2 -M cell cycle arrest in cancer cells, and induce the intrinsic apoptosis pathway.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Digestive System Inflammation | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > AP-1 | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-121607
• CAS No.: 881046-01-1
• Molecular Formula: C22H23N7
• Molecular Weight: 385.46
• Purity: 99.28%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (6.49 mM); Clear solution
• Availability: In-stock

Source

Original product source