Tanomastat (BAY 12-9566) is an orally bioavailable, non-peptidic biphenyl matrix metalloproteinases (MMPs) inhibitor with a Zn-binding carboxyl group. The K i values are 11, 143, 301, and 1470 nM for MMP-2 , MMP-3 , MMP-9 , MMP-13 respectively. Tanomastat shows anti-invasive and antimetastatic activity in several experimental tumor models.
Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > MMP
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