Dynarrestin

Overview

Dynarrestin is a aminothiazole inhibitor of cytoplasmic dyneins 1 and 2 . Dynarrestin rapidly and reversibly inhibits dynein 1-driven microtubule gliding in vitro plus a range of dynein 1- and 2-dependent processes in cells without affecting ATP hydrolysis and interfering with ciliogenesis. Dynarrestin suppresses hedgehog (Hh) -dependent proliferation of neuronal precursors and tumor cells.

Application

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Product Information

• Catalog No.: HY-121802
• CAS No.: 2222768-84-3
• Molecular Formula: C22H23F2N3O2S
• Molecular Weight: 431.50
• Purity: 98.18%
• Storage: 4°C, protect from light * The compound is unstable in solutions, freshly prepared is recommended.
• Solubility: 10 mg/mL (23.17 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source