SCH 2047069

Overview

SCH 2047069 (MK-8267) is an orally active kinesin spindle protein ( KSP ) inhibitor ( K d : 0.5 nM) that can cross the blood-brain barrier. SCH 2047069 exhibits an IC 50 value of ≤ 5 nM against the KSP ATPase . SCH 2047069 exhibits broad-spectrum antitumor activity. SCH 2047069 can induce mitotic arrest and apoptosis in tumor cells. SCH 2047069 can be used in the research of tumors such as ovarian cancer , colon cancer , glioblastoma, and lymphoma.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Cytoskeleton | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Kinesin | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-122130
• CAS No.: 1146209-50-8
• Molecular Formula: C20H17F4N3O2S
• Molecular Weight: 439.43
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source