OSU-03013 is a Celecoxib ( HY-14398 ) analog. OSU-03013 can promote apoptosis , up-regulate E-cadherin , and down-regulate β-catenin , c-myc , Wnt1 , and N-cadherin . OSU-03013 reduces cell migration and invasion. OSU-03013 regulates both Wnt and mTOR expression to inhibit colon cancer (CC) cell proliferation. OSU-03013 can be used for CC cancer research.
Products | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Colorectal Cancer | Products > Disease Areas > Digestive System Cancer | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Cytoskeleton | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > c-Myc | Products > Signaling Pathways > mTOR | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Cadherin | Products > Signaling Pathways > β-catenin | Products > Signaling Pathways > Wnt
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