USP7-IN-2 (compound 4) is a non-competitive USP7 inhibitor with an IC 50 of 6 nM. USP7-IN-2 causes degradation of MDM2 , stabilization of p53 and induction of p21 in multiple cell lines, and can be utilized in cancer research.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Deubiquitinase | Products > Signaling Pathways > MDM-2/p53
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