K02288 (GMP) is K02288 ( HY-12278 ) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. K02288 is a potent bone morphogenetic protein (BMP) type I receptor inhibitor with IC 50 s of 1.8, 1.1, 6.4 nM for ALK1 , ALK2 and ALK6 , respectively. K02288 shows slightly weaker inhibition against ALK3 and ALK6 with IC 50 s of of 5-34 nM.
Products | Products > GMP Small Molecules | Products > Disease Areas > Cancer | Products > Signaling Pathways > TGF-beta/Smad | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > TGF-β Receptor
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