Umbralisib hydrochloride

Overview

Umbralisib (TGR-1202) hydrochloride is an orally active, potent and selective dual PI3Kδ and casein kinase-1-ε ( CK1ε ) inhibitor, with EC 50 of 22.2 nM and 6.0 μM, respectively. Umbralisib hydrochloride exhibits unique immunomodulatory effects on chronic lymphocytic leukemia (CLL) T cells. Umbralisib hydrochloride can be used for haematological malignancies reseach.

Application

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Product Information

• Catalog No.: HY-12279C
• CAS No.: 1532533-78-0
• Molecular Formula: C31H25ClF3N5O3
• Molecular Weight: 608.01
• Purity: 99.04%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (4.11 mM); Clear solution
• Availability: In-stock

Source

Original product source