ZT-12-037-01

Overview

ZT-12-037-01 is a STK19-targeted inhibitor, has a high-affinity interaction with STK19 protein and inhibits oncogenic NRAS-driven melanocyte malignant transformation. ZT-12-037-01 is an ATP -competitive inhibitor, inhibiting phosphorylation of NRAS (major isoform of Ras family) with an IC 50 of 24 nM.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Ras

Product Information

• Catalog No.: HY-122866
• CAS No.: 2328073-61-4
• Molecular Formula: C21H31N5O2
• Molecular Weight: 385.50
• Purity: 98.06%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: 5 mg/mL (12.97 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source