Kenpaullone

Overview

Kenpaullone is a potent inhibitor of CDK1/cyclin B and GSK-3β , with IC 50 s of 0.4 μM and 23 nM, and also inhibits CDK2/cyclin A, CDK2/cyclin E, and CDK5/p25 with IC 50 s of 0.68 μM, 7.5 μM, 0.85 μM, respectively. Kenpaullone, a small molecule inhibitor of KLF4 , reduces self-renewal of breast cancer stem cells and cell motility in vitro.

Application

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Product Information

• Catalog No.: HY-12302
• CAS No.: 142273-20-9
• Molecular Formula: C16H11BrN2O
• Molecular Weight: 327.18
• Purity: 98.20%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (7.64 mM); Suspended solution
• Availability: In-stock

Source

Original product source