SC-68448

Overview

SC-68448 (S 448) is a selective αvβ3 antagonist ( IC 50 = 1 nM). SC-68448 inhibits αvβ3-mediated endothelial cell proliferation. SC-68448 reduces the total level of αvβ6 in NHBE cells. SC-68448 inhibits angiogenesis in a rat corneal neoplasia model. SC-68448 inhibits tumor growth and completely prevents the development of hypercalcemia in a rat Ledich cell tumor model. SC-68448 can be used in research on cardiovascular and cerebrovascular diseases such as hypercalcemia and cancers such as testicular interstitial cell tumors.

Application

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Product Information

• Catalog No.: HY-123864
• CAS No.: 188804-07-1
• Molecular Formula: C19H19Cl2N5O4
• Molecular Weight: 452.29
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source