RU-302

Overview

RU-302 is a pan TAM inhibitor that blocks the interface between the TAM Ig1 ectodomain and the Gas6 Lg domain. RU-302 effectively blocks Gas6-inducible Axl receptor activation with a low micromolar IC 50 in cell assays, and suppresses lung cancer tumor growth.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Lung Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > TAM Receptor

Product Information

• Catalog No.: HY-124066
• CAS No.: 1182129-77-6
• Molecular Formula: C24H24F3N3O2S
• Molecular Weight: 475.53
• Purity: 98.72%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 2.5 mg/mL (5.26 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source