4'-Bromo-resveratrol

Overview

4'-Bromo-resveratrol (4′‐BR) is a dual SIRT1 / SIRT3 inhibitor with an IC 50 of 0.2 mM for both targets. 4'-Bromo-resveratrol induces caspase -dependent apoptosis , induces G0/G1 cell cycle arrest, and inhiibits proliferation. 4'-Bromo-resveratrol reduces lactate production, glucose uptake, and NAD + /NADH ratio, and downregulates lactate dehydrogenase A and glucose transporter 1 ( GLUT1 ). 4'-Bromo-resveratrol can be used for the research of melanoma.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Digestive System Inflammation | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Metabolic Disease | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Lactate Dehydrogenase | Products > Signaling Pathways > GLUT | Products > Signaling Pathways > Sirtuin | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Caspase

Product Information

• Catalog No.: HY-124113
• CAS No.: 1224713-90-9
• Molecular Formula: C14H11BrO2
• Molecular Weight: 291.14
• Purity: 99.94%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Availability: In-stock

Source

Original product source