Voruciclib hydrochloride

Overview

Voruciclib hydrochloride is an orally active and selective CDK inhibitor with K i values of 0.626 nM-9.1 nM. Voruciclib hydrochloride potently blocks CDK9 , the transcriptional regulator of MCL-1 . Voruciclib hydrochloride represses expression of MCL-1 in multiple models of diffuse large B-cell lymphoma (DLBCL).

Application

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Product Information

• Catalog No.: HY-12422A
• CAS No.: 1000023-05-1
• Molecular Formula: C22H20Cl2F3NO5
• Molecular Weight: 506.30
• Purity: 99.26%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.08 mg/mL (4.11 mM); Clear solution
• Availability: In-stock

Source

Original product source