TBK1/IKKε-IN-4

Overview

TBK1/IKKε-IN-4 is a 6-aminopyrazolopyrimidine derivative and a potent, selective TBK1 and IKKε inhibitor with IC 50 values of 13 nM and 59 nM, respectively. TBK1/IKKε-IN-4 shows 100- to 1000-fold less activity against other protein kinases including PDK1, PI3K family members and mTOR .

Application

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Product Information

• Catalog No.: HY-124652
• CAS No.: 1381930-17-1
• Molecular Formula: C28H35N7O4
• Molecular Weight: 533.62
• Purity: 99.42%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 4.75 mg/mL (8.90 mM); Clear solution
• Availability: In-stock

Source

Original product source