PIK-C98

Overview

PIK-C98 is a potent and selective PI3K inhibitor, with IC 50 s of 0.59, 1.64, 3.65, and 0.74 μM for α , β , δ , and γ isoforms , respectively. PIK-C98 inhibits all class I PI3Ks but has no effects on AKT or mTOR activity. PIK-C98 interferes with the ATP-binding pockets of PI3Ks by forming H-bonds and arene-H interactions with specific amino acid residues. PIK-C98 induces apoptosis by inhibiting PI3K . PIK-C98 can be used for the research of multiple myeloma.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PI3K | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-12491
• CAS No.: 691388-62-2
• Molecular Formula: C16H10Cl2N2OS
• Molecular Weight: 349.23
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source