QM31

Overview

QM31 (SVT016426), a cytoprotective agent, is a selective inhibitor of Apaf-1 . QM31 inhibits the formation of the apoptosome (IC 50 =7.9μM), the caspase activation complex composed by Apaf-1, cytochrome c, dATP and caspase-9. QM31 exerts mitochondrioprotective functions and interferes with the intra-S-phase DNA damage checkpoint.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Caspase

Product Information

• Catalog No.: HY-125018
• CAS No.: 937735-00-7
• Molecular Formula: C39H38Cl4N4O4
• Molecular Weight: 768.56
• Purity: 95.00%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (2.71 mM); Clear solution
• Availability: In-stock

Source

Original product source