ZEN-3694

Overview

ZEN-3694 (Compound 146) is a BET inhibitor. ZEN-3694 inhibits hlL-6 mRNA transcription (IC 50 ≤0.3 uM), and c-myc activity in human AML MV4-11 cell (IC 50 ≤0.3 uM). ZEN-3694 inhibits tetra-acetylated histone H4 binding to BRD4 bromodomain 1 (IC 50 ≤0.3 uM).

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Epigenetic Reader Domain

Product Information

• Catalog No.: HY-125236
• CAS No.: 1643947-30-1
• Molecular Formula: C19H19N5O
• Molecular Weight: 333.39
• Purity: 99.85%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (7.50 mM); Clear solution
• Availability: In-stock

Source

Original product source