RO5353

Overview

RO5353 is an orally active inhibitor for p53-MDM2 with an IC 50 of 7 nM for MDM2 . RO5353 inhibits the proliferation of wild-type p53 cancer cells with an average IC 50 of 7 nM. RO5353 exhibits antitumor efficacy and good pharmacokinetic characteristics in mice.

Application

Products | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > MDM-2/p53

Product Information

• Catalog No.: HY-12580
• CAS No.: 1360821-61-9
• Molecular Formula: C29H29Cl2FN4O4S
• Molecular Weight: 619.53
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source