MS31 trihydrochloride

Overview

MS31 trihydrochloride is a potent, highly affinity and selective fragment-like methyllysine reader protein spindlin 1 (SPIN1) inhibitor. MS31 trihydrochloride potently inhibits the interactions between SPIN1 and H3K4me3 ( IC 50 =77 nM, AlphaLISA; 243 nM, FP ). MS31 trihydrochloride selectively binds Tudor domain II of SPIN1 ( K d =91 nM). MS31 trihydrochloride potently inhibits binding of trimethyllysine-containing peptides to SPIN1, and is not toxic to nontumorigenic cells.

Application

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Product Information

• Catalog No.: HY-125837A
• CAS No.: 2748239-18-9
• Molecular Formula: C20H30Cl3N3O2
• Molecular Weight: 450.83
• Purity: 98.0%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source