4-Hydroxyretinoic acid

Overview

4-Hydroxyretinoic acid (4-HRA) is a derivative of Retinoic acid ( HY-14649 ). 4-Hydroxyretinoic acid is formed via the catalysis of retinol by cytochrome P-450 isoenzymes. 4-Hydroxyretinoic acid also serves as a substrate for UDP-glucuronosyltransferase (s) and recombinant UGT2B7 . 4-Hydroxyretinoic acid binds to the nuclear receptor RAR (Retinoic Acid Receptor), activates RAR and RXR-alpha, subsequently regulates gene expression and cell differentiation, and induces cancer cell apoptosis ( Apoptosis ). 4-Hydroxyretinoic acid also participates in multiple physiological processes such as immunoregulation, neuroprotection and antioxidation.

Application

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Product Information

• Catalog No.: HY-125904
• CAS No.: 66592-72-1
• Molecular Formula: C20H28O3
• Molecular Weight: 316.43
• Purity: 94.58%
• Storage: -80°C, protect from light, stored under nitrogen
• Availability: In-stock

Source

Original product source