Prucalopride succinate

Overview

Prucalopride succinate is an orally active, selective and specific 5-HT 4 receptor agonist (high affinity), with pK i s of 8.6 and 8.1 for human 5-HT4a/4b receptors , respectively. Prucalopride succinate improves intestinal motility by promoting regeneration of the intestinal nervous system in rats. Prucalopride succinate also shows anticancer activity by blocking of the PI3K/AKT/mTor signaling pathway. Prucalopride succinate can be used in studies of chronic constipation, pseudo-intestinal obstruction and cancer .

Application

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Product Information

• Catalog No.: HY-12694
• CAS No.: 179474-85-2
• Molecular Formula: C22H32ClN3O7
• Molecular Weight: 485.96
• Purity: 99.94%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (5.14 mM); Clear solution
• Availability: In-stock

Source

Original product source