Genz-123346 free base

Overview

Genz-123346 free base is an orally available inhibitor of glucosylceramide synthase . Genz-123346 blocks the conversion of ceramide to glucosylceramide (GL1) and inhibits GM1 with an IC 50 of 14 nM.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Glucose Metabolism | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Metabolic Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Glucosylceramide Synthase (GCS)

Product Information

• Catalog No.: HY-12744
• CAS No.: 491833-30-8
• Molecular Formula: C24H38N2O4
• Molecular Weight: 418.57
• Purity: 99.57%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 3 mg/mL (7.17 mM); Clear solution
• Availability: In-stock

Source

Original product source