Netarsudil hydrochloride

Overview

Netarsudil (AR-13324) hydrochloride is a competitive inhibitor of Rho-associated protein kinases ( ROCK I and ROCK II ) and a reversible inhibitor of the norepinephrine transporter ( NET ). Netarsudil hydrochloride reduces intraocular pressure by inhibiting ROCK , causing relaxation of trabecular meshwork cells and dilation of episcleral veins, thereby increasing the ease of aqueous humor outflow, while inhibiting NET to reduce aqueous humor production. Netarsudil hydrochloride is mainly used in the study of ocular hypertension and primary open-angle glaucoma.

Application

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Product Information

• Catalog No.: HY-12798B
• CAS No.: 1253952-02-1
• Molecular Formula: C28H29Cl2N3O3
• Molecular Weight: 526.45
• Purity: 99.90%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source